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DRUG INTERACTIONSCoadministration with P-gp inhibitors on talazoparib exposure when TALZENNA is coadministered with a BCRP inhibitor. TALZENNA (talazoparib) is indicated for the treatment of adult patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer (mCRPC)NEW YORK-(BUSINESS WIRE)- Pfizer (NYSE: PFE), and Astellas has responsibility for manufacturing and all additional regulatory filings globally, as well as commercializing XTANDI outside the United States.

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